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Clearsynth is a leading innovator in pharmaceutical reference standards, offering high-quality Reference Standards for Ruxolitinib, including both pharmacopeial and non-pharmacopeial impurities, metabolites, stable isotope products, and nitrosamines (N-NO products). Our Ruxolitinib impurity reference standards are invaluable for pharmaceutical research, supporting product development, ANDA and DMF submissions, quality control (QC), method validation, and stability studies. They also aid in identifying unknown impurities and assessing genotoxic potential.
Our Ruxolitinib-related products undergo thorough characterization and are supplied with detailed Certificates of Analysis (COA) and analytical data that meet regulatory requirements. All supplied products are re-tested at regular intervals to ensure ongoing quality and compliance.

Ruxolitinib Related Compounds

Stable Isotopes

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
Deuruxolitinib Stable Isotopes CS-O-53404 1513883-39-0 Enquire
rac-Ruxolitinib-13C,15N2 Stable Isotopes CS-T-98815 Not Available Enquire
rac-Ruxolitinib-d8 Stable Isotopes CS-O-11948 1794791-38-0 Enquire
rac-Ruxolitinib-d9 (major) Stable Isotopes CS-T-93835 941688-05-7 (unlabelled) In Stock
Ruxolitinib D4 Stable Isotopes CS-AU-00068 1513883-31-2 Enquire
Ruxolitinib D9 Stable Isotopes CS-EO-02963 Not Available Enquire


API Standards

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
Ruxolitinib API Standards CS-T-61211 941678-49-5 In Stock
Ruxolitinib Benzoate API Standards CS-O-51552 Not Available In Stock
Ruxolitinib Fumarate API Standards CS-O-51568 Not Available In Stock
Ruxolitinib Hemifumarate API Standards CS-O-45668 2803478-47-7 In Stock


Metabolites

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
3-keto cyclopentyl Ruxolitinib Metabolites CS-O-56723 1809535-64-5 Enquire
Rac-Ruxolitinib N-Hydroxymethyl Impurity Metabolites CS-O-48150 Not Available Enquire


Impurities

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
(+)-Di-p-anisoyl-D-tartaric Acid Impurities CS-U-00085 191605-10-4 Enquire
(S)-3-(4-Bromo-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile Impurities CS-O-56859 2183286-19-1 Enquire
(S)-Ruxolitinib Phosphate Impurities CS-EO-03841 2703484-89-1 Enquire
5-hydroxymethyl Ruxolitinib impurity Impurities CS-O-45346 Not Available Enquire
Rac-5-hydroxymethyl Ruxolitinib Impurity Impurities CS-O-51494 Not Available Enquire
Rac-Ruxolitinib 5,6-dihydroxyimpurity Impurities CS-O-57196 1289219-47-1 Enquire
Rac-Ruxolitinib 5-oxo-impurity Impurities CS-O-57195 1289218-88-7 Enquire
Rac-Ruxolitinib 6-amino-4-pyrimidinyl impurity Impurities CS-O-57194 Not Available Enquire
Rac-Ruxolitinib 6-hydroxy-5-oxo-impurity Impurities CS-O-57193 1289219-34-6 Enquire
Rac-Ruxolitinib Acid impurity Impurities CS-O-39659 3016399-21-3 Enquire
Rac-Ruxolitinib Acrylo pyrimidine Impurity Impurities CS-EO-01361 941685-39-8 In Stock
Rac-Ruxolitinib N-acetylymethyl impurity Impurities CS-O-48151 Not Available Enquire
Rec-Ruxolitinib Amide Impurity Impurities CS-T-93931 1911644-32-0 Enquire
Ruxolitinib Acid Amine Impurity Impurities CS-O-44181 2606144-44-7 In Stock
Ruxolitinib Acid impurity Impurities CS-EO-01901 2102675-40-9 In Stock
Ruxolitinib acid Phosphate salt Impurities CS-O-45234 2102675-40-9(Freebase ) Enquire
Ruxolitinib Amide Impurity Impurities CS-O-46525 2102675-42-1 In Stock
Ruxolitinib carboxamide impurity Impurities CS-O-47310 Not Available Enquire
Ruxolitinib Dibenzoyl SME Pyrimidine Impurity Impurities CS-O-48149 1236033-04-7 Enquire
Ruxolitinib dimethylamine impurity Impurities CS-O-47311 Not Available Enquire
Ruxolitinib Hydroxy Impurity Impurities CS-EO-01131 1187595-89-6 Enquire
Ruxolitinib Impurity 27 Impurities CS-O-59755 Not Available Enquire
Ruxolitinib Impurity 28 Impurities CS-O-58859 1236033-23-0 Enquire
Ruxolitinib Impurity 37 Impurities CS-O-58348 Not Available Enquire
Ruxolitinib Impurity 4 Impurities CS-EO-01362 941685-37-6 (free base) Enquire
Ruxolitinib Impurity 51 Impurities CS-O-56382 3029006-61-6 Enquire
Ruxolitinib Impurity 7 Impurities CS-EO-02149 2606144-45-8 In Stock
Ruxolitinib M18 Impurities CS-O-38557 1315607-85-2 In Stock
Ruxolitinib M27 Impurities CS-O-38558 1809535-63-4 Enquire
Ruxolitinib Methyl ester impurity Impurities CS-O-45667 2950130-23-9 In Stock
Ruxolitinib N-1 Intermediate Impurities CS-O-60076 1236033-02-5 Enquire
Ruxolitinib N-Methanol Impurities CS-T-96005 1236033-03-6 Enquire
Ruxolitinib N-Oxide Impurity 1 Impurities CS-EO-02343 Not Available In Stock
Ruxolitinib N-Oxide Impurity 2 Impurities CS-O-59014 Not Available Enquire
Ruxolitinib Phosphate Impurities CS-T-61212 1092939-17-7 In Stock
Ruxolitinib propanamide Impurity Impurities CS-O-59756 Not Available Enquire
Ruxolitinib SEM impurity Impurities CS-O-46675 941685-40-1 In Stock
RUXOLITINIB SEM TARTARIC ACID S-ISOMER Impurities CS-O-46354 Not Available Enquire
Ruxolitinib SEM-Sulfonyl Impurity Impurities CS-EO-01132 187594-13-3 Enquire
Ruxolitinib S-isomer Oxalate Impurities CS-EO-03842 1883417-29-5 Enquire
Ruxolitinib Vinyl dimer impurity Impurities CS-O-46540 Not Available Enquire
Ruxolitinib, SEM Pyrimidine Impurity Impurities CS-M-24045 941685-27-4 In Stock
Ruxolitinib-7-(((2-(trimethylsilyl)ethoxy)methoxy)methyl)-im... Impurities CS-O-56930 Not Available Enquire


Intermediates

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
rac-Ruxolitinib Intermediates CS-T-85501 941688-05-7 Enquire
Ruxolitinib Impurity 29 Intermediates CS-O-59757 Not Available Enquire
S-Ruxolitinib Intermediates CS-T-51507 941685-37-6 Enquire


Building Blocks

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
4-{7H-pyrrolo[2,3-d]pyrimidin-4-yl}-1H-pyrazole Building Blocks CS-TA-55998 952518-97-7 Enquire